ITGB1BP2 Antibody, FITC conjugated

Code CSB-PA892333LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ITGB1BP2 Polyclonal antibody
Uniprot No.
Target Names
ITGB1BP2
Alternative Names
ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role during maturation and/or organization of muscles cells.
Gene References into Functions
  1. Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress. PMID: 12496958
  2. Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy PMID: 23124043
  3. The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI. PMID: 21546274
  4. Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed PMID: 20017903
Tissue Specificity
Expressed in skeletal and cardiac muscles but not in other tissues.
Database Links

HGNC: 6154

OMIM: 300332

KEGG: hsa:26548

STRING: 9606.ENSP00000362935

UniGene: Hs.109999

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